Serratus Plane Block For Breast Reduction Surgery (SPB)

Ataturk University

Status and phase: Completed; Phase 4

Conditions: Pain Management

Treatments: Drug: Bupivacaine; Drug: Saline

Study type: Interventional

Funder types: Other

Identifiers

NCT02930733

AUTF ANESTHESIA3

Details and patient eligibility

About

Serratus plane block was first described in 2013 by Blanco and designed to primarily block the thoracic intercostal nerves. And this block provides sufficient analgesia lateral anterior and posterior part of thoracic wall.Increased use of ultrasound guidance for regional anesthesia in recent years has led to definition of thoracic wall PECs blocks by Blanco. The Serratus plain block (SPB), providing wider analgesia, with easier application and less adverse effects than neuroaxial blocks, has been defined after these blocks and has taken its place in the literature.In spite of the insufficient randomized clinical trials in the literature, SPB has been reported for many cases such as thoracoscopy, shoulder arthroscopy, breast surgery and axillary lymph node dissections, and the results are promising. The aim of this study is to determine effectiveness of ultrasound guided bilateral serratus plane block in patients undergoing breast reduction surgery.

Main outcome measures: The primary endpoint is postoperative opioid consumption.

Secondary endpoints are visual analogue pain scores, opioid related side effects.

Enrollment: 40 patients

Sex: Female

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• American Society of Anesthesiologist's physiologic state I-III patients undergoing breast reduction surgery

Exclusion criteria

• chronic pain
• bleeding disorders
• renal or hepatic insufficiency
• patients on chronic non-steroidal anti-inflammatory medications
• emergency cases

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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40 participants in 2 patient groups, including a placebo group

ultrasound guided serratus plane block

Active Comparator group

Description:

Bilateral ultrasound guided serratus plane block with 30 ml %0,25 bupivacaine

Treatment:

Drug: Bupivacaine

ultrasound guided sham block

Placebo Comparator group

Description:

Bilateral ultrasound guided sham block with 2 ml saline subcutaneously

Treatment:

Drug: Saline