Serum AMH Levels in Patients Who Underwent Hypogastric Artery Ligation

Kanuni Sultan Suleyman Training and Research Hospital

Status: Completed

Conditions: AMH

Treatments: Procedure: hypogastric artery ligation

Study type: Observational

Funder types: Other

Identifiers

NCT03220594

1826

Details and patient eligibility

About

To observe the effects of hypogastric artery ligation on serum antimullerian hormone levels.

Full description

To measure and compare serum antimullerian hormone levels in patients who underwent hypogastric artery ligation/ hypogastric artery ligation+ hysterectomy and postpartum control. The procedures performed as an emergency life saving method during delivery. The reasons for hypogastric artery ligation/ hypogastric artery ligation+ hysterectomy were obstetric hemorrhage mainly uterine atony.

The serum levels of antimullerian hormone were measured 6 months after the operations and compared with matching postpartum controls. Serum levels of FSH, LH, PRL and TSH were also measured 6 months after the operation. Further, antral follicle count measured along with the aforementioned blood tests.

Enrollment: 90 patients

Sex: Female

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• age 18- 40 years
• no systemic or endocrine diseases
• patients who had hypogastric artery ligation and/or hysterectomy
• healthy postpartum patients as controls

Exclusion criteria

• history of chemotherapy and/or radiotherapy
• Obese patients
• patients with previous/present endometriosis
• patients with PCOS

Trial design

90 participants in 3 patient groups

Hypogastric artery ligation (HAL)

Description:

Patients who underwent only hypogastric artery ligation performed during the delivery of their babies. Six months after the operation they will evaluated for their ovarian reserve via hormones and astral follicle count (AFC)

Treatment:

Procedure: hypogastric artery ligation

HAL and hysterectomy

Description:

Patients who underwent both hypogastric artery ligation and hysterectomy performed during the delivery of their babies. Six months after the operation they will evaluated for their ovarian reserve via hormones and astral follicle count (AFC)

Treatment:

Procedure: hypogastric artery ligation

Postpartum

Description:

Postpartum control group constituted of patients delivered baby without any complication and evaluated 6 months later.