Serum Amyloid A in Women With Unexplained Infertility

Ain Shams Maternity Hospital

Status: Completed

Conditions: Infertility

Treatments: Other: Serum amyloid A level

Study type: Observational

Funder types: Other

Identifiers

NCT03918200

SAAI

Details and patient eligibility

About

High follicular fluid amyloid A level is associated with reduced pregnancy rate.

The aim of this study was to find an association between serum level of amyloid A and unexplained infertility.

Enrollment: 90 patients

Sex: Female

Ages: Under 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. women with unexplained infertility (unprotected, regular intercourse for at least 2 years).

2. Nulligravida ,Regular mensturation.

3. Age less than 40 years .

4. Normal parameters (in the study group):

   • hormonal profile (day 2 FSH,LH), midluteal phase progesterone, Prolactin, TSH
   • transvaginal ultrasound
   • hysterosalpingography
   • detailed semen analysis

Exclusion criteria

1. Age above 40

2. Smoking females

3. Obesity (BMI>30)

4. Women with any systemic or medical diseases leads to elevation of SAA as:

   1. Systemic lupus erythematosis
   2. Rheumatoid arthritis
   3. Sarcoidosis
   4. Diabetes Mellitus

5. Using hormonal contraception (for control group)

Trial design

90 participants in 2 patient groups

Study

Description:

Women with unexplained infertility

Treatment:

Other: Serum amyloid A level

Control

Description:

Fertile women who had normal physical and pelvic examination, regular menstrual cycles, don't use hormonal contraceptive, had one child at least.

Treatment:

Other: Serum amyloid A level