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Serum CPK and Creatinine Changes During Plyometric Training in Collegiate Athletes

B

Batterjee Medical College

Status

Completed

Conditions

Plyometric Exercises
Exercise Physiology
Creatine Kinase
Muscle Damage

Treatments

Behavioral: Lower Body Plyometric Training
Other: control group

Study type

Interventional

Funder types

Other

Identifiers

NCT07356193
BMC-CPK-Study-2023

Details and patient eligibility

About

This retrospective study evaluated the effects of an eight-week lower body plyometric training program on serum creatine phosphokinase (CPK) and creatinine levels in male collegiate volleyball players. Sixty two players were divided into experimental and control groups. CPK and creatinine were measured at baseline and multiple time points during training. The study assessed whether plyometric training produced harmful biochemical changes or signs of rhabdomyolysis.

Full description

This study evaluated the physiological effects and safety of an eight-week lower body plyometric training program in male collegiate volleyball players, focusing on changes in serum creatine phosphokinase (CPK) and creatinine levels. Sixty two healthy athletes were randomly assigned to either a plyometric training group or a control group. The experimental group performed progressive lower body plyometric exercises twice weekly for eight weeks, while the control group continued regular volleyball training.

Serum CPK and creatinine were assessed at baseline and multiple time points throughout the intervention. CPK levels in the training group increased significantly early in the program, peaking on Day 4 and remaining elevated until Week 2, before returning to baseline by Week 8. Importantly, all values remained within normal clinical ranges, and no signs of rhabdomyolysis or overtraining were observed. Serum creatinine levels showed no significant changes, indicating preserved renal function. No biomarker changes were detected in the control group.

These findings indicate that an eight-week, progressively designed plyometric training program is safe and well tolerated in male collegiate volleyball players.

Enrollment

62 patients

Sex

Male

Ages

18 to 20 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • male collegiate volleyball players
  • Age: 18-20 years
  • No prior plyometric training

Exclusion criteria

  • History of kidney disease
  • Current musculoskeletal injury
  • neuromuscular impairments

Trial design

Primary purpose

Prevention

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

62 participants in 2 patient groups

Lower Body Plyometric Training
Experimental group
Treatment:
Other: control group
Behavioral: Lower Body Plyometric Training
Control Group
Active Comparator group
Treatment:
Other: control group

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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