Serum Ferritin and Hepicidin Concentration in Chronic Periodontitis Patients With T2DM

Fayoum University

Status: Completed

Conditions: Periodontitis; Type2 Diabetes

Study type: Observational

Funder types: Other

Identifiers

NCT03964428

fayoum dentistry

Details and patient eligibility

About

serum level of ferritin and hepicidin were evaluated in periodontitis patient with and without type 2 diabetes before and after non surgical periodontal treatment to clarify their in periodontal disease

Enrollment: 60 patients

Sex: All

Ages: 30 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients with more than 30% of the sites had clinical attachment level (CAL) 3-4mm with T2DM
• systemically healthy patients with more than 30% of the sites had clinical attachment level (CAL) 3-4mm
• healthy subjects had clinically healthy gingiva with ≤ 3mm pocket probing depth (PPD), nearly zero plaque index (PI), gingival index (GI), zero CAL.

Exclusion criteria

• (I) Pregnancy or lactation, (II) History of receiving professional periodontal treatment during the past 6 months; (III) Treatment with any type of medications and/ or antibiotics during the past 3 months and (IV) Current or former smokers.

Trial design

60 participants in 3 patient groups

periodontitis

periodontitis with T2DM

control