Serum Hs-CRP in Periodontitis Patients With or Without Diabetes

Cairo University (CU) logo

Cairo University (CU)

Status

Completed

Conditions

Diabetes Mellitus, Type 2
Periodontal Disease

Treatments

Procedure: Scaling and root planing

Study type

Interventional

Funder types

Other

Identifiers

NCT03908606
1281976

Details and patient eligibility

About

the aim of this study was to assess serum levels of high sensitivity c reactive protein in periodontitis patients with and without type 2 diabetes in a trial to analyze its prognostic effect following non-surgical periodontal therapy.

Full description

Periodontitis and diabetes are chronic disorders with a two-way correlation as they can both stimulate an inflammatory response with subsequent formation of inflammatory mediators and cytokines. C reactive protein is an inflammatory plasma marker having a role in the systemic reaction to inflammation. thus, our aim in the current study was to evaluate serum levels of high sensitivity c reactive protein in periodontitis patients with and without type 2 diabetes in a trial to analyze its prognostic effect following non-surgical periodontal therapy. A total of 60 patients were enrolled in this study. ELISA was used for determination of hs- CRP. Non- surgical periodontal therapy was carried out for all periodontitis patients.

Enrollment

60 patients

Sex

All

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Diabetic patients type 2
  • Periodontitis patients

Exclusion criteria

  • Smokers
  • Pregnant females

Trial design

Primary purpose

Diagnostic

Allocation

Non-Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

60 participants in 3 patient groups

Periodontitis patients with diabetes type 2
Experimental group
Description:
scaling and root planing was administered to all patients. Serum samples were collected before and after treatment to assess hs-CRP levels. Glycated hemoglobin was measured before and after treatment
Treatment:
Procedure: Scaling and root planing
Periodontitis patients
Experimental group
Description:
scaling and root planing will be done to periodontitis patients. Serum samples were collected before and after treatment to assess hs-CRP levels.
Treatment:
Procedure: Scaling and root planing
Healthy control group
No Intervention group
Description:
We measured serum levels of hs-CRP in all healthy control subjects

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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