Serum Lipid Levels and Lp-PLA2 in Chronic Periodontitis

Meenakshi Ammal Dental College and Hospital

Status

Completed

Conditions

Chronic Periodontitis (Disorder)

Treatments

Diagnostic Test: serum lipid levels and Lp-PLA2

Study type

Observational

Funder types

Other

Identifiers

NCT03041480

MADC/IRB/2015/91

Details and patient eligibility

About

To assess the association between periodontal parameters, serum lipid profile and Lp-PLA2 level in systemically healthy Chronic Periodontitis subjects and healthy controls.

Full description

Seventy five participants were divided into 3 groups. The groups consisted of GROUP I- generalized severe chronic periodontitis, GROUP II- generalized moderate chronic periodontitis and GROUP III- systemically and periodontally healthy volunteers who served as control. The selected patients were then evaluated for periodontal parameters, lipid profile and Lp-PLA2.

Enrollment

75 patients

Sex

All

Ages

35 to 64 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Group I:

Subjects with age ≥ 35 years.
Presence of at least 24 teeth, with Clinical attachment loss (CAL) ≥ 5mm in more than 30% of sites.

Group II:

Subjects with age ≥ 35 years.
Presence of at least 24 teeth, with Clinical attachment loss (CAL) between 3-4 mm in more than 30% of sites.

Group III:

Subjects with age ≥ 35 years.
Healthy and intact periodontium

Exclusion criteria

Presence of any systemic disease or conditions that could affect periodontal tissues.
History of periodontal treatment in past 6 months.
Smoking and alcoholism
Anomalies of blood and immune system
Systemic medication or antibiotic treatment for the previous 6 months.
Pregnant females.