Serum Lipid Profile and Lip Squamous Cell Carcinoma

Akdeniz University

Status

Completed

Conditions

Lipids

Lipid Profile

SCC - Squamous Cell Carcinoma

Lip Cancer

Oral Cancer

Study type

Observational

Funder types

Other

Identifiers

NCT07005115

22032023/250

Details and patient eligibility

About

The goal of this observational retrospective study is to assess whether serum lipid levels differ between patients diagnosed with lip squamous cell carcinoma (SCC) and healthy individuals. The study aims to evaluate if alterations in lipid parameters, especially LDL levels, are associated with the presence of lip SCC and could serve as potential early biomarkers.

The main research questions are:

Do patients with lip SCC show significantly lower LDL levels compared to healthy controls? Are there significant differences in total cholesterol (TC), triglycerides (TG), HDL, and VLDL between the two groups? A retrospective analysis was conducted using existing medical records of patients with lip SCC and healthy subjects obtained from 2018-2023.

Full description

Demographic data and lipid profile information were collected from 56 patients (28 lip SCC and 28 healthy). The lipid parameters included were total cholesterol (TC), triglycerides (TG), high density lipoprotein (HDL), low density lipoprotein (LDL) and very low-density lipoprotein (VLDL).

Enrollment

56 patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

patients clinically evident and histopathologically confirmed with lip SCC (study group)
subjects without any underlying systemic disease (control group)

Exclusion criteria