Serum Magnesium Level in Type 2 Diabetes Mellitus

Sohag University

Status

Not yet enrolling

Conditions

Diabetes Mellitus

Treatments

Diagnostic Test: Magnesium

Study type

Observational

Funder types

Other

Identifiers

NCT06059833

Soh-Med-23-07-14MS

Details and patient eligibility

About

Diabetes mellitus (DM) is a chronic metabolic disorder characterized by persistent hyperglycemia. It may be due to impaired insulin secretion, resistance to peripheral actions of insulin, or both . Chronic hyperglycemia in synergy with the other metabolic aberrations in patients with diabetes mellitus can cause damage to various organ systems, leading to the development of disabling and life-threatening health complications, most prominent of which are microvascular (retinopathy, nephropathy, and neuropathy) and macrovascular complications leading to a 2-fold to 4-fold increased risk of cardiovascular diseases Mg2+ deficiency is usually identified by the measurement of serum Mg2+ concentration. Hypomagnesemia is defined by a serum Mg2+ concentration < 0.75 mmol/L, but a deficiency due to low dietary intake in otherwise healthy people is uncommon. Although overt signs of clinical Mg2+ deficiency are not routinely recognized in the healthy population, relatively low Mg2+ intake and/or Mg2+ status have been shown to be associated with chronic diseases, including cardiovascular disease, T2DM, osteoporosis, pulmonary disease, depression, migraine headaches, inflammation, and cancer

Enrollment

120 estimated patients

Sex

Female

Ages

30+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

• Type 2 Diabetes Mellitus according to WHO criteria.

Exclusion criteria

• Renal failure patients.
- Type I DM patients.
- Acute pancreatitis.
- Hyperthyroidism.
- Hyperparathyroidism.
- Malignancies.
- Patients on loop/thiazide diuretics.
- Patients on Mg supplement.
- Patients on Mg containing antacids.
- Any other conditions causing low Mg levels were excluded from the study.