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Serum Magnesium Levels in Desalination Tap Water and Outcomes in Acute Myocardial Infarction Patients

S

Sheba Medical Center

Status

Completed

Conditions

Death
Acute-MI
Myocardial Infarction
Cardiovascular Disease
Congestive Heart Failure

Study type

Observational

Funder types

Other

Identifiers

NCT02356393
SHEBA-14-1545-MS-CTIL

Details and patient eligibility

About

Association between serum magnesium and clinical outcome in patients with acute MI (AMI) with 1 year follow-up in 300 patients in regions supplied by desalinated drinking water (DSW) (Sheba MC) and 150 patients in regions with non-desalinated drinking water (DW) (Nahariya MC).

Full description

Extensive seawater desalination in Israel may decrease magnesium in drinking water (DW), causing hypomagnesemia and adverse health effects. We study the association between consumption of desalinated drinking water (DSW) and serum magnesium in acute MI (AMI) patients, Subjects 35-75 years of age with the first AMI will be prospectively recruited during 1 year from 2 regions; the Departments of Cardiology at the Sheba Medical center (300 patients, predominantly served by DSW) and the Nahariya Medical Center (150 patients, served by non-DSW). Questionnaire will be developed to collect data on demographic variables (at home and work), water and beverages consumption habits (tap water, mineral water), dietary sources of Mg and Mg supplementations. Mg levels will be measured in DW from the patients' homes and in their serum on admission.

Enrollment

150 patients

Sex

All

Ages

35 to 75 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  1. Patients with first AMI
  2. Age 35-75

Exclusion criteria

  1. Patients > age 75

Trial contacts and locations

1

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Central trial contact

Michael Shechter, MD; Shlomi Matetzky, MD

Data sourced from clinicaltrials.gov

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