Serum Progesterone on the Day of Embryo Transfer and Pregnancy Rate.

Instituto Valenciano de Infertilidad, IVI VALENCIA

Status: Completed

Conditions: Ongoing Pregnancy Rate

Treatments: Diagnostic Test: Analysis of serum Progesterone in blood sample

Study type: Observational

Funder types: Other

Identifiers

NCT03272412

1704-VLC-024-EL

Details and patient eligibility

About

This study aims to analyze whether serum Progsterone levels on the day of Embryo Transfer are related with Ongoing Pregnancy rate in artificial endometrial preparation cycles with intravaginal micronized progesterone.

Enrollment: 1,205 patients

Sex: Female

Ages: 18 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria

1. Age <50 years old

2. Hormonal Replacement therapy cycle for embryo transfer in any of the following situations:

   1. Embryos in fresh cycle with donated oocytes.
   2. Subsequent embryo transfers of vitrified embryos in cycles of donated oocytes.
   3. Frozen embryo transfers in cycles with autologous oocytes.

3. Endometrial line: >6.5-7mm (with trilaminar aspect) in proliferative phase, before introducing progesterone.

4. Administration of natural micronized progesterone intravaginally (400 mg/12 hours for 5 complete days (10 dosis), before the embryo transfer and maintained until pregnancy week 12.

5. Embryo transfer of blastocyst (day 5-6).

6. Signed Informed Consent

Exclusion Criteria

1. Uterine pathology (submucous o intramural fibroids (>4 cm) or which deform the uterine cavity; endometrial polyps or Müllerian anomalies; or adnexal anomalies (communicating hydrosalpinx).
2. Simultaneous participation in another clinical study.
3. Participation in another clinical study before the inclusion in the present study, and which could affect the objectives of the present study.