Serum Regucalcin Level and Chronic Hepatitis B

K

Konya Meram State Hospital

Status

Completed

Conditions

Chronic Hepatitis b
Liver Fibrosis

Treatments

Diagnostic Test: Serum regucalcin level

Study type

Interventional

Funder types

Other

Identifiers

NCT05435599
10542 (Registry Identifier)

Details and patient eligibility

About

This study, it was aimed to investigate the relationship between serum regucalcin level and liver fibrosis level in patients with CHB infection.

Full description

Chronic hepatitis B (CHB) infection continues to be an important health problem due to its high morbidity and mortality. For this reason, it is very important to determine the appropriate timing to start antiviral therapy in patients with CHB infection and to evaluate the stage of liver fibrosis in the treatment follow-up. Liver biopsy is the gold standard for detecting liver fibrosis. Although it is generally accepted to be a safe procedure, it can cause some serious complications. For this reason, in recent years, many studies have been conducted on new noninvasive tests in the evaluation of liver fibrosis. One of them is the serum regucalcin level. Studies have shown that serum regucalcin levels increase in liver damage, but there is no study in the literature comparing liver fibrosis and serum regucalcin levels in CHB infection. This study, it was aimed to investigate the relationship between serum regucalcin level and liver fibrosis level in patients with CHB infection.

Enrollment

120 patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Being followed up with a diagnosis of chronic hepatitis B Not having a known history of liver disease who applied to our outpatient clinic for other reasons Having a liver biopsy ≥18 years

Exclusion criteria

<18 years

Trial design

Primary purpose

Diagnostic

Allocation

Non-Randomized

Interventional model

Single Group Assignment

Masking

Quadruple Blind

120 participants in 2 patient groups

Chronic Hepatitis B
Other group
Description:
Measurement of serum regucalcin level
Treatment:
Diagnostic Test: Serum regucalcin level
Healthy Volunteers
Other group
Description:
Measurement of serum regucalcin level
Treatment:
Diagnostic Test: Serum regucalcin level

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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