Serum Squamous Cell Carcinoma Antigen Level and Tumor Volume in Head and Neck Cancer

Prince of Songkla University

Status: Completed

Conditions: Head and Neck Cancer

Treatments: Other: Non-interventional study

Study type: Observational

Funder types: Other

Identifiers

NCT02879968

PrinceSongklaU

Details and patient eligibility

About

Correlation between serum squamous cell carcinoma antigen level and tumor volume in Head and Neck Cancer is to determine a correlation between level of serum squamous cell carcinoma antigen and tumor volume in Head and Neck Caner measured by cross-sectional imaging.

Full description

The study is a cross-sectional study. A single measurement of serum squamous cell carcinoma antigen level is performed in the eligible Head and Neck squamous cell carcinoma patients.

The study tool measuring serum squamous cell carcinoma antigen level is ARCHITECT SCC (Abbott).

The gross tumor volume in the cross sectional imaging obtained within 2 weeks of each patient is calculated with the typical ellipsoid formula.

Correlation between both parameters will be determined.

Enrollment: 52 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Histologically proven squamous cell carcinoma in Head and Neck
• Getting a cross-sectional imaging of Head and Neck within 2 weeks of collecting serum squamous cell carcinoma antigen

Exclusion criteria

• Metastatic disease
• Accompanied Non-Head and Neck squamous cell carcinoma
• Nasopharyngeal, thyroid, salivary, nose and paranasal sinus carcinoma
• Skin disease: eczema, erythrodermic epidermitis, pemphigus, and psoriasis
• Pulmonary disease: tuberculosis, adult respiratory distress syndrome, pulmonary infiltration with eosinophilia, sarcoidosis, and bronchogenic cyst
• Renal failure
• Using antihistamine eye drops

Trial design

52 participants in 1 patient group

Head and Neck squamous cell carcinoma

Description:

A single measurement of serum squamous cell carcinoma antigen level is performed in the eligible Head and Neck squamous cell carcinoma patients. The study tool measuring serum squamous cell carcinoma antigen level is ARCHITECT SCC (Abbott). The gross tumor volume in the cross sectional imaging obtained within 2 weeks of each patient is calculated with the typical ellipsoid formula.

Treatment:

Other: Non-interventional study