Serum YKL-40 Level and Platelets Indices Among Patients With Diabetic Erectile Dysfunction

Aswan University

Status and phase: Completed; Phase 4

Conditions: Erectile Dysfunction; Erectile Dysfunction With Diabetes Mellitus

Treatments: Drug: Tadalafil 5mg

Study type: Interventional

Funder types: Other

Identifiers

NCT05446493

346/3/19

Details and patient eligibility

About

The aim of this current study is to estimate serum level of YKL-40, serum total testosterone and platelets indices in diabetic patients with erectile dysfunction treated by daily tadalafil 5mg for 3 months.

Enrollment: 60 patients

Sex: Male

Ages: 30 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Diabetic patients with ED.

Exclusion criteria

• Patients with history of pelvic trauma.
• Patients with major pelvic surgical intervention.
• Patients with hypogonadism and hyperprolactinemia.
• Patients with chronic liver disease.
• Patients with cardio vascular system diseases.
• History of chronic intake of central nervous system, anti androgen drugs or other drugs as Tramadol.
• Smokers patients.
• Patients with non-vasculogenic Erectile dysfunction.

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

Tadalafil group

Active Comparator group

Description:

Each patient will be treated by tadalafil 5mg daily for 3months

Treatment:

Drug: Tadalafil 5mg

control group

No Intervention group

Description:

Estimation of serum YKL-40, platelet indices and serum total testosterone in healthy individuals in camparing with tadalafil group