Serum Zinc, Peptic Ulcer Disease and H. Pylori Infection

Ain Shams University

Status: Completed

Conditions: Peptic Ulcer Disease

Treatments: Procedure: Upper gastrointestinal endoscopy

Study type: Observational

Funder types: Other

Identifiers

NCT02716025

811

Details and patient eligibility

About

Fifty consecutive patients with symptoms suggestive of peptic ulcer disease were included. All underwent complete clinical evaluation, laboratory investigations, upper gastrointestinal endoscopy and rapid urease test. Measurement of serum zinc level was done for all the included patients in addition to twenty five age and sex matched healthy control subjects.

Enrollment: 75 patients

Sex: All

Ages: 18 to 55 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Symptoms suggestive of peptic ulcer disease like epigastric pain, dyspepsia, heartburn

Exclusion criteria

• Patients who received zinc supplementation, proton pump inhibitors (PPI), non-steroidal anti-inflammatory drugs (NSAIDs)
• Those presented with hematemesis or melena
• Those with chronic liver disease, renal failure, malabsorption or previous gastric surgery

Trial design

75 participants in 2 patient groups

Case Group

Treatment:

Procedure: Upper gastrointestinal endoscopy

Control Group