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Inclusion and exclusion criteria
Severe/Cerebral Malaria:
Uncomplicated malaria:
Sepsis:
Clinical signs of infection in combination with any two of the following signs:
Negative peripheral blood slide for any stages of malaria parasites or a negative rapid diagnostic test for falciparum and vivax malaria
[As bacterial culture is not routinely available at the study site, positivity of cultures is not required]
Age > 12 years
Full informed written consent obtained
Acidosis:
Clinical suspicion of metabolic acidosis in combination with any of the following:
Negative peripheral blood slide for any stages of malaria parasites or a negative rapid diagnostic test for falciparum and vivax malaria; and not meeting any of the inclusion criteria for sepsis as stated above.
Age > 12 years
Full informed written consent obtained
Encephalitis:
Healthy volunteers:
Exclusion Criteria:
840 participants in 6 patient groups
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Data sourced from clinicaltrials.gov
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