Severe and Transient Hypoxemia During Selective Intra-arterial Chemotherapy for Retinoblastoma in Children: Evaluation of the Right-sided Heart Function.

Christian Kern

Status: Unknown

Conditions: Retinoblastoma

Treatments: Diagnostic Test: Trans-thoracic echocardiography

Study type: Observational

Funder types: Other

Identifiers

NCT03559894

2017-01539

Details and patient eligibility

About

Children having selective ophthalmic artery chemotherapy for retinoblastoma under general anaesthesia may experience troubles during the procedure. The troubles are transient, may be severe and include hypoxemia, hypotension and bradycardia. All children having such trouble always fully recovered without any sequelae or prolonged length of stay. The investigators suspect that these phenomenons are caused by transient pulmonary hypertension.The objective is to see whether transient pulmonary hypertension and right-sided heart failure is present during theses phenomenon by trans-thoracic echocardiography.

Enrollment: 50 estimated patients

Sex: All

Ages: Under 6 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Retinoblastoma requiring selective ophthalmic artery chemotherapy under general anaesthesia

Exclusion criteria

• Obesity
• pre-existing significant heart or pulmonary disease.