Severe Cutaneous Adverse Reactions in Thailand (ThaiSCAR)

Chulalongkorn University

Status: Unknown

Conditions: Steven-Johnson Syndrome; Toxic Epidermal Necrolysis; Acute Generalized Exanthematous Pustulosis; Generalized Bullous Fixed Drug Eruption; Drug Reaction With Eosinophilia and Systemic Symptoms

Study type: Observational

Funder types: Other

Identifiers

NCT02574988

Chula-ARC 001/15

Details and patient eligibility

About

The multicenter registry of patients with severe cutaneous adverse reactions among tertiary medical institutes in Thailand to study clinical characteristics, etiologies, therapeutic outcomes, quality of life, and the values of in vitro drug allergy diagnosis for the confirmation of the causative drugs

Full description

Patients with severe cutaneous adverse reactions (Steven-Johnson Syndrome, toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms, acute generalized exanthematous pustulosis, and generalized bullous fixed drug eruption) among six tertiary medical institutes in Thailand will be recruited to study clinical characteristics, etiologies, therapeutic outcomes, quality of life, and the values of using laboratory techniques for the confirmation of the causative drugs

Enrollment: 200 estimated patients

Sex: All

Ages: 15+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients fulfilled criteria of probable or definite cases of SJS, TEN, DRESS, or AGEP according to RegiSCAR validation criteria as well as patients diagnosed with GBFDE

Exclusion criteria

• Patients later confirmed to have other diagnosis than diseases mentioned above or have no sufficient data for the registry

Trial design

200 participants in 1 patient group

SCAR Patients

Description:

Patients diagnosed with severe cutaneous adverse reactions with be recruited