Severe Intraocular Infection

University Hospital, Strasbourg, France

Status: Completed

Conditions: Endophthalmitis

Treatments: Biological: Cytokines dosage in Aqueous humor

Study type: Observational

Funder types: Other

Identifiers

NCT02818062

3964

Details and patient eligibility

About

The host-immune reaction to infection is essential for the comprehension of the disease and the development of new therapies.

The aim of the study is to describe intraocular cytokines network in aqueous humor using multiplex immunoassay, during severe intraocular infection.

Enrollment: 263 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Post-operative endophthalmitis
• Cataract

Exclusion criteria

• None

Trial design

263 participants in 2 patient groups

Endophthalmitis

Description:

The diagnosis of endophthalmitis was made on the basis of clinical features including pain, decreased visual acuity (VA), diffuse bulbar conjunctival hyperaemia, chemosis, inflammation of the anterior segment and posterior segment inflammation (all patients had vitreous infiltration diagnosed by biomicroscopy or ophthalmic ultrasound).

Treatment:

Biological: Cytokines dosage in Aqueous humor

Cataract (Control)

Description:

Controls were patients who underwent cataract surgery.

Treatment:

Biological: Cytokines dosage in Aqueous humor