Severe Pandemic H1N1 Infection in ICU: Comparative Resource Utilization

University of Manitoba

Status: Completed

Conditions: Novel H1N1 Influenzal Acute Respiratory Infection

Treatments: Other: We will compare the resources used by both groups

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT01485237

H2009:175 (Other Identifier)

pandemic001

Details and patient eligibility

About

The main purpose of this study is to review the resource utilization of severe adult H1N1 pneumonia undergoing antiviral and oxygen therapy, mechanical ventilation and support with pulmonary rescue therapies ( nitric oxide, ECMO, HFO) in critically ill patients in Winnipeg. Secondary objectives include, comparison of resource utilization to other similar disorders (viral pneumonia, bacterial pneumonia, septic shock, ARDS). The investigators will also look at the percentage of patients that required ICU care as compared to those who could be cared for on medical wards. The investigators will determine the resources used by both groups and compare. Finally the investigators will record the frequency of chronic comorbidities in hospitalized adult H1N1 patients.

Enrollment: 400 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. > 18years,
2. Suspected or confirmed influenza (Appendix A)
3. Requirement for ICU admission due to respiratory distress or critical illness defined as one of:a) Inspired oxygen need of >50% for at least 4 hours (For FiO2 for non-intubated patients see Appendix B) b) mechanical ventilation c) Patient is receiving inotrope or vasopressor

Exclusion criteria

1. Age less than 18 years

Trial design

400 participants in 2 patient groups

Severe H1N1 pneumonia in adult patients

Description:

Severe adult H1N1 pneumonia patients undergoing antiviral and oxygen therapy, mechanical ventilation and support with pulmonary rescue therapies ( nitric oxide, ECMO, HFO)in Winnipeg

Treatment:

Other: We will compare the resources used by both groups

Severe pneumonia in adults not H1N1

Description:

Patients admitted to the hospital and/or ICU with viral pneumonia, bacterial pneumonia, septic shock, ARDS in Winnipeg

Treatment:

Other: We will compare the resources used by both groups