Sevoflurane in Electroconvulsive Therapy

Inonu University

Status and phase: Completed; Phase 4

Conditions: ECT; Anesthesia

Treatments: Drug: sevorane

Study type: Interventional

Funder types: Other

Identifiers

NCT01905904

ulkü_2

Details and patient eligibility

About

The purpose of the study was to investigate the effects of different doses of sevoflurane used in electroconvulsive therapy (ECT) on duration of seizure, hemodynamic response and recovery profiles

Full description

Motor (EMG) and electroencephalography seizure duration (EEG), heart rate (HR) and mean arterial pressure (MAP) values, and recovery times were recorded.

Enrollment: 25 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Study included 25 patients of American Society of Anesthesiologists (ASA) physical status I-II aged between 18-60 years who were scheduled for ECT sessions under general anesthesia

Exclusion criteria

• Pregnancy
• Cerebrovascular disease
• Epilepsy
• Unstable cardiovascular disease
• Chronic obstructive pulmonary disease; and
• Renal or hepatic failure

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Triple Blind

---

25 participants in 2 patient groups

sevorane

Active Comparator group

Description:

Sevorane 4% concentration during anesthesia induction

Treatment:

Drug: sevorane

sevorane %7

Active Comparator group

Description:

Sevorane 7% concentration during anesthesia induction

Treatment:

Drug: sevorane