Sevoflurane, Propofol, Postoperative Pain

Tampere University Hospital

Status and phase: Completed; Phase 4

Conditions: Healthy Adults; Gynecological Disease

Treatments: Drug: Propofol; Drug: Sevoflurane

Study type: Interventional

Funder types: Other

Identifiers

NCT01437462

Satu_Pokkinen_01_2011

Details and patient eligibility

About

The impact of anaesthetic method (intravenous vs. inhalational) has been proposed, but not proven in a large-scale study. The researchers aim to provide an investigation that has sufficient power to clarify the potential effect of anaesthetic method on postoperative need of opioids. Sevoflurane and propofol will be compared.

Enrollment: 168 patients

Sex: Female

Ages: 18 to 69 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age 18-69 years
• Gender: female
• ASA status 1-3
• Laparoscopic hysterectomy

Exclusion criteria

• Body Mass Index over 35
• Diabetes mellitus
• Liver disease
• Allergies to pharmaceuticals used in the Study
• Present use of opioids

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind