Sevoflurane Versus Propofol in Endovascular Coiling of Cerebral Aneurysm

Tongji Hospital

Status: Completed

Conditions: Propofol; Sevoflurane

Treatments: Drug: Anesthesia Agent

Study type: Observational

Funder types: Other

Identifiers

NCT06666959

SW-001 (Other Identifier)

TJ-IRB20230413

Details and patient eligibility

About

The goal of this observational study is to learn about the anti-inflammatory effects of anesthetics on patients undergoing endovascular coiling of cerebral aneurysm. The main question it aims to answer is:

Does sevoflurane or propofol affect the inflammatory response in subarachnoid hemorrhage?

Participants already undergoing endovascular coiling of cerebral aneurysm will have their serum levels of inflammatory factors measured.

Enrollment: 80 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Consecutive patients aged 18 years and older presenting to the Tongji hospital for endovascular coiling of cerebral aneurysm were eligible for enrollment.

Exclusion criteria

• have an endocrine system disease
• pregnancy
• have other brain disorders
• take drugs that alter endocrine hormones
• receive perioperative blood derivatives

Trial design

80 participants in 1 patient group

patients undergoing endovascular coiling of cerebral aneurysm in Tongji hospital

Description:

The present clinical study was carried out with the aim of determine whether the inflammatory effect differs when using propofol or sevoflurane anesthesia.

Treatment:

Drug: Anesthesia Agent