Sex-Based Differences of LA: Impact on AF Ablation.

Quirónsalud

Status

Not yet enrolling

Conditions

Atrial Fibrillation (AF)

Treatments

Procedure: Atrial fibrillation ablation

Study type

Observational

Funder types

Other

Identifiers

NCT07159685

Sex-Tailored By-LAWT AF

Details and patient eligibility

About

The aim of the study is to assess sex-related differences in patients who underwent a first ablation procedure for paroxysmal or persistent AF, guided by the personalized ablation strategy of the BY-LAWT protocol. Specifically, to compare anatomical characteristics, procedural parameters, and clinical outcomes between sexes.

Enrollment

700 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients who underwent a first ablation procedure for atrial fibrillation (paroxysmal or persistent).
Availability of an adequate pre-procedural cardiac CT scan for LAWT, LAV and inFAT analysis.
Availability of complete procedural data, including ablation index (AI) values recorded using the SmartTouch catheter (Biosense Webster).
Availability of 12-month follow-up data for efficacy and safety endpoint evaluation.
Ablation performed according to the by-LAWT protocol

Exclusion criteria

Age < 18 years.
Previous cardiac ablation (including AF ablation or other arrhythmias).
Incomplete data regarding procedural parameters, or follow-up.
Poor quality pre-procedural cardiac MDCT
Ablation not performed according to the BY-LAWT protocol.
Structural heart disease (e.g., dilated cardiomyopathy, valvular heart disease with surgical indication) that could substantially influence atrial dimensions or ablation response.