Sex-specific Differences in AAA Complexity

Imperial College London

Status

Not yet enrolling

Conditions

AAA - Abdominal Aortic Aneurysm

Treatments

Diagnostic Test: CTA Aorta

Study type

Observational

Funder types

Other

Identifiers

NCT05399706

292985

Details and patient eligibility

About

A retrospective cohort study of computed tomography scans of AAA patients considered for repair, in order to identify sex specific differences in abdominal aortic aneurysm (AAA) metrics and the association between anatomical differences/features of complexity and adverse patient outcome.

Full description

A retrospective cohort study of computed tomography scans of AAA patients considered for repair.

The study aims to, firstly, identify sex specific differences in abdominal aortic aneurysm (AAA) metrics utilising manual and automated image processing techniques; and secondly, if numbers are sufficient, explore the association between features of AAA complexity and adverse patient outcome.

Enrollment

1,000 estimated patients

Sex

All

Ages

50+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

All adult patients with AAA receiving assessment +/- primary open or endovascular repair at participating centre from 1/1/2010 to 31/12/2020.
Must have AAA >= 5cm.
Must have CT imaging within 1 year of operation or definitive turn down for treatment.

Exclusion criteria

Insufficient CT imaging quality (>3mm slices) or lack of CT within 1 year of operation.
Insufficient clinical data to establish risk factors or clinical outcomes.
Ruptured aneurysm, aorto-iliac occlusive disease, isolated iliac aneurysm, penetrating aortic ulcer, dissection, juxta or supra-renal aneurysm.
Secondary repair/not primary treatment decision for AAA repair.