SGB in Management of Patients With PDPH Using TCD

Zagazig University

Status: Completed

Conditions: Post-Dural Puncture Headache

Treatments: Drug: Sphenopalatine Ganglion Block using 2% lidocaine

Study type: Interventional

Funder types: Other

Identifiers

NCT04401878

6140

Details and patient eligibility

About

This study aims to investigate the ability of SPGB in the management of PDPH. Transcranial Doppler is also used as an measure to assess the block success by detecting the variability in the cerebral hemodynamics before and after the block.

Full description

This clinical trial is performed in postoperative orthopedic unit. In this study, 120 patients were enrolled who had an epidural anesthesia; 60 patients who developed PDPH joined the treatment group (A) and received the SP block. They are assessed before the procedure by NRS and at 30 mins, 2h, 4h, 6h, 12h, and 24h after the procedure. Patients are also assessed by TCD before and after the block. The control group (B) included 60 patients with no PDPH.

Enrollment: 120 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients are considered who had an epidural anesthesia
• Patients with ASA 1 and 2
• Patients' age ranged from 18 to 60 years.

Exclusion criteria

• Patients with septal perforation, nasal septum deviation,or nasal bleeding.
• Patients have recent nasal trauma
• Patients have recent nasal surgery
• Patients have a nasal infection
• Patients within ASA 3 and 4
• Patients older than sixty yrs or younger than eighteen yrs.

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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120 participants in 2 patient groups

the treatment group (A)

Experimental group

Description:

Patients who have PDPH are manged by SPGB, they are assessed by NRS before the block, at 30 mins, 2h, 4h, 6h, 12h, and 24hours after block. The patients are also examined by TCD before and after the block.

Treatment:

Drug: Sphenopalatine Ganglion Block using 2% lidocaine

control group (B)

Experimental group

Description:

The control group (B) of 60 patients with no PDPH were examined by TCD

Treatment:

Drug: Sphenopalatine Ganglion Block using 2% lidocaine