Shanghai Atrial Fibrillation Registry (SAFE)

Shanghai Jiao Tong University

Status: Invitation-only

Conditions: Atrial Fibrillation (AF)

Treatments: Procedure: catheter ablation, left atrial appendage closure

Study type: Observational

Funder types: Other

Identifiers

NCT06802965

XHEC-C-2024-220-1

Details and patient eligibility

About

Using the Shanghai Municipal Health Commission database and Shanghai Centers for Disease Control and Prevention database, patients with AF in Shanghai are included to construct the Shanghai AF registry to investigate clinical characteristics, treatment, and prognosis.

Full description

1. To determine the most suitable risk stratification model for Chinese AF population regarding stroke and major cardiovascular events, i.e. CHA2DS2-VASc, CHA2DS2-VASc-60, or CHA2DS2-VA scores.
2. To compare the clinical prognosis of patients with AF receiving the combined procedure of catheter ablation and left atrial appendage closure (LAAC), single catheter ablation, and single LAAC.

Enrollment: 400,000 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• With diagnosis of AF: the diagnosis must be identified from the Shanghai Municipal Health Commission database and verified by 12-lead ECG or Holter monitoring since 2015
• Residents of Shanghai
• Taking part in the government-issued health insurance, including the Urban Residents' Basic Medical Insurance (URBMI), the Urban-Employ Based Medical Insurance (UEBMI) and the New Rural Cooperative Medical Scheme (NRCMS).

Exclusion criteria

• Non-residence of Shanghai
• Without the government-issued health insurance
• Die at the day of index diagnosis of AF

Trial design

400,000 participants in 1 patient group

Patients with AF

Description:

All patients with a diagnosis of AF and residents of Shanghai are included.

Treatment:

Procedure: catheter ablation, left atrial appendage closure