Shivering Control After Percutaneous Nephrolithotomy

Assiut University

Status and phase: Completed; Phase 3

Conditions: Shivering Control

Treatments: Drug: Aminoacid; Drug: Magnesium sulfate

Study type: Interventional

Funder types: Other

Identifiers

NCT04695613

17300539

Details and patient eligibility

About

Aim of the study is comparing the effect of amino acid versus magnesium sulfate infusion on postoperative shivering in patients undergoing elective percutaneous nephrolithotomy surgery under general anesthesia.

Full description

A written informed consent was taken from the patients. Patients were assigned randomly to two groups (40 subjects each) to be anesthetized and infused with either an iv amino acid starting just before and during anesthesia (group A) or an iv magnesium sulphate starting just before and during anesthesia (group M) in the perioperative period.

Enrollment: 80 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ASA I-II who were listed for elective percutaneous nephrolithotomy PCNL surgery under general anesthesia.

Exclusion criteria

• Hepatic inefficiency
• Renal inefficiency
• Spinal anesthesia because of a different mechanism of hypothermia

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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80 participants in 2 patient groups

aminoacid group

Active Comparator group

Description:

patients received an IV amino acid infusion 150 ml/kg/hr starting just before and during anesthesia

Treatment:

Drug: Aminoacid

magnesium sulfate group

Active Comparator group

Description:

patients received an IV magnesium sulphate bolus and infusion 40 mg/kg starting just before and during anesthesia

Treatment:

Drug: Magnesium sulfate