Short- and Long-term Outcomes of Stenting for Symptomatic Intracranial Arterial Stenosis: a Cohort Study

Sohag University

Status: Completed

Conditions: Intracranial Atherosclerosis

Study type: Observational

Funder types: Other

Identifiers

NCT05203887

Soh-Med-22-01-10

Details and patient eligibility

About

The purpose of this study is to assess short and long term outcomes of stenting for symptomatic intracranial arterial stenosis.

Enrollment: 43 patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Participants had a symptomatic intracranial stenosis of 70-99 percentage (%) with a lesion length of ≤15 mm and target vessel diameter of ≥2.0 mm in the intracranial internal carotid, middle cerebral, intracranial vertebral or basilar arteries and the measurements of stenosis will be made on magnetic resonance angiography (MRA) using the Warfarin-Aspirin Symptomatic Intracranial Disease (WASID) trial method and confirmed by digital subtraction angiography (DSA).
• Presented with transient ischemic attack (TIA) or stroke within the past 12 months attributed to the stenosis.

Exclusion criteria

• Participants with acute infarctions within the past 3 weeks.
• Severe arterial tortuosity prevents the deployment of endovascular devices.
• Non-atherosclerotic lesion on magnetic resonance imaging (MRI), embolic or perforator stroke on MRI or computerized tomography (CT).
• A baseline modified Rankin Scale (mRS) score of >3.
• Massive cerebral infarction (>1/2 middle cerebral artery (MCA) territory), intracranial hemorrhage, epidural or sub-dural hemorrhage, and intracranial brain tumor on CT or MRI scan.