Short Pulse and Q-switched ND-YAG Laser With Topical Carbon Versus Fractional CO2 Laser for Enlarged Facial Pores

Cairo University (CU)

Status: Completed

Conditions: Skin Lesion

Treatments: Device: short pulse and Q-switched ND-YAG laser with topical carbon; Device: fractional CO2 laser

Study type: Interventional

Funder types: Other

Identifiers

NCT04470466

las49

Details and patient eligibility

About

Facial pores are visible topographic features of the skin that reflect openings of pilosebaceous follicles, that may be enlarged causing distress to some individuals. Many patients desire treatment for this condition, which can be an early sign of skin aging. Therapeutic modalities include intense pulsed light, radiofrequency, dermabrasion, oral and topical retinoids, as well as chemical peeling. Lasers, as fractional CO2, short pulse and Q-switched Nd-YAG, can potentially be used in treatment of wide pores.

This study aims at the assessment and comparison of therapy with short pulsed and Q-switched Nd-YAG laser plus topical carbon with fractional CO2 laser in the management of wide facial pores.

Full description

topical carbon cream will be applied to one side of the face in patients with wide facial pores, followed by 2 passes of short pulse 1064 ND:YAG laser, then one pass of Q-switched ND-YAG laser.

fractional CO2 laser will be performed to the other half of the face. the patients will receive 2 treatment sessions

Enrollment: 30 patients

Sex: All

Ages: 18 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Participants who are more than 18 years old with the large facial pores and are aware of their problem and seeking treatment

Exclusion criteria

• • Previous laser therapy, chemical peeling, microdermabrasion or cosmetic procedure for the face.

  • Patients with any contraindication to laser therapy such as photosensitive diseases, skin malignancies, patients on oral retinoids.
  • Keloid-forming tendency.
  • Local or systemic treatment for skin pores in the previous 3 months
  • Connective tissue disease or the use of immunosuppressive medications.
  • Pregnancy.
  • Present or past history of herpes labialis.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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30 participants in 2 patient groups

short pulse and Q-switched ND-YAG laser with topical carbon

Active Comparator group

Treatment:

Device: short pulse and Q-switched ND-YAG laser with topical carbon

Fractional CO2 Laser

Active Comparator group

Treatment:

Device: fractional CO2 laser