Short Term and Day to Day Reproducibility of Reflectometric Measurement of Retinal Oxygen Saturation in Healthy Subjects

Medical University of Vienna

Status: Withdrawn

Conditions: Ocular Physiology

Treatments: Device: Measurement of oxygen saturation of retinal vessels with optical reflectometer

Study type: Observational

Funder types: Other

Identifiers

NCT00991900

OPHT-030409

Details and patient eligibility

About

Adequate perfusion and oxygenation is essential for the function of the inner retina. Although this is a well known fact, measurement of oxygen saturation in the eye is still a delicate and not fully explored task. However, recently a new instrument for the non-invasive measurement of retinal vessel oxygen saturation has been introduced. Unfortunately, no data about reproducibility in humans is yet available for this instrument. Consequently, the current study seeks to evaluate the short term and day to day reproducibility of retinal vessel oxygenation in healthy volunteers.

20 healthy volunteers will be included and oxygen saturation of retinal vessels will be determined. The reproducibility of the results will be tested by repeated measurements and the collected data will be independently analyzed by two observers.

Sex: All

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Men and Women aged between 18 and 35 years,
• Nonsmokers
• Body mass index between 15th and 85th percentile
• Normal ophthalmic findings, ametropia < 3 Dpt.

Exclusion criteria

• Regular use of medication, abuse of alcoholic beverages, participation in a clinical trial in the 3 weeks preceding the study
• Treatment in the previous 3 weeks with any drug except oral contraceptives
• Symptoms of a clinically relevant illness in the 3 weeks before the study day
• Blood donation during the previous 3 weeks

Trial design

0 participants in 1 patient group

Healthy subjects

Treatment:

Device: Measurement of oxygen saturation of retinal vessels with optical reflectometer