Short Term Effects of Increasing Sleep Duration

Lifespan

Status and phase: Completed; Phase 2

Conditions: Overweight and Obesity

Treatments: Behavioral: No change in sleep; Behavioral: Sleep Duration

Study type: Interventional

Funder types: Other

Identifiers

NCT01428687

U01CA150387 (U.S. NIH Grant/Contract)

U01CA150387 - Study 2

Details and patient eligibility

About

A series of studies are proposed to develop an intervention to increase sleep duration and study the effects on eating, exercise, and weight control. The hypothesis is that increasing sleep duration will help improve weight loss and maintenance.

Full description

Study 1 is conducted in a sleep laboratory. Participants sleep short duration (approximately four hours per night) on one weekend and long duration (approximately nine hours per night) on another weekend.

Study 2 is examining ways to increase sleep duration in overweight individuals with short sleep and examining the effects on short term weight loss.

Study 3 is comparing a standard weight loss program with a novel Sleep+Weight Loss intervention.

Enrollment: 60 patients

Sex: All

Ages: 25 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• age 25 to 45;
• BMI 25 to 50;
• healthy;
• sleep 6.5 hours or less per night

Exclusion criteria

• use of sleep medications;
• sleep apnea;
• third shift worker

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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60 participants in 3 patient groups

Increase Sleep Gradually

Active Comparator group

Description:

Subjects in this condition are taught to increase their sleep by 30 minutes per night during week 1 of the intervention; 60 minutes during week 2; and 90 minutes during week 3. Following the sleep intervention, these participants receive a standard behavioral with loss intervention.

Treatment:

Behavioral: Sleep Duration

Increase Sleep Immediately

Active Comparator group

Description:

Subjects in this condition are taught to increase their sleep by 90 minutes per night starting in week 1. Following the sleep intervention, these participants receive a standard behavioral with loss intervention.

Treatment:

Behavioral: Sleep Duration

No Intervention: Control Group

Active Comparator group

Description:

This group is told to make no changes in their sleep habits. Following the sleep intervention, these participants receive a standard behavioral with loss intervention.

Treatment:

Behavioral: No change in sleep