Short-term Effects of Intravitreal Bevacizumab and Triamcinolone in Patients With Diabetic Macular Edema

Insel Gruppe AG, University Hospital Bern

Status: Completed

Conditions: Diabetic Macular Edema

Study type: Observational

Funder types: Other

Identifiers

NCT00563940

KEK E: 29-03-07

AUG 044/07

Details and patient eligibility

About

Diabetic macular edema is a common complication of ocular diabetes mellitus and can cause blindness. Hypoxygenation of the retina stimulates tissue mediators, especially different subtypes of vascular endothelial growth factor (VEGF). VEGF is responsible for proliferation, extension and increased permeability of the vessels. The aim of our study was to examine the short-term effect of intravitreal bevacizumab (Avastin® 1.25 mg in 0.05 ml) and triamcinolone on visual acuity and central retinal thickness in patients with clinically significant diabetic macular edema (CSME).

Enrollment: 30 patients

Sex: All

Ages: 20 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• clinical significant macular edema

Exclusion criteria

• retinal thickness < 250 µm

Trial design

30 participants in 2 patient groups

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