Short-term Evaluation of Motor and Sensory Function in Post-COVID-19 Patients

Assiut University

Status: Completed

Conditions: Sensory Neuropathy; Motor Neuropathy

Study type: Observational

Funder types: Other

Identifiers

NCT05721040

Covid-19 NCS

Details and patient eligibility

About

SARS-COV-2 infection reframed medical knowledge in many aspects, yet there is still a lot to be discovered. our aim is to evaluate neurological impact of covid-19; if there is any.

Full description

Coronavirus disease 19 (COVID-19) can cause neuropsychiatric, psychological and psychosocial impairments. Literature regarding the sensory and motor affection of COVID-19 is still limited.

Public health emergencies as COVID-19 are likely to cause adverse neuropsychiatric impacts. Cognitive impairments after SARS-COV-2 infection were noticed, COVID-19 patients complain of poor concentration, declined memory, and insomnia, as well as anxiety and depression symptoms.

in a study; Neurological manifestations described in 36.4% of 214 patients with confirmed COVID-19. However, the symptoms described [dizziness (not further defined), headache, and impaired consciousness] are commonplace in many severe infections and represent disturbances in neurological function rather than a neurological disease per se. Anosmia and ageusia have received much attention, but are ubiquitous in other common upper respiratory tract infections. While a reported increased risk of cerebrovascular disease.

Enrollment: 40 patients

Sex: All

Ages: 20 to 68 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients with confirmed RT-PCR COVID-19 infection with mild to moderate severity based on the Egyptian ministry of health (MOH) protocol (version 1.4, November 2020) with neurological symptoms suggestive of peripheral neuropathy

Exclusion criteria

• patients presenting with neurological manifestations other than peripheral neuropathy, such as stroke, cerebral hemorrhage, encephalitis, or meningitis.
• Patients with any medical condition or comorbidities that may affect the result of the study as diabetes, arthritis, and carpel tunnel syndrome.
• Severe COVID-19 patients with a critical condition that needs hospitalization and ventilatory support were also excluded from the study.

Trial design

40 participants in 2 patient groups

Covid-19 Group

Description:

Motor nerve study was performed in the median and posterior tibial nerve to assess the motor function of the upper and lower limbs. Sensory nerve study was done for the median and sural nerves to estimate the peripheral neurological function of both upper and lower limbs. F wave study was performed for the upper limb in the median nerve.

Control Group

Description:

Motor nerve study was performed in the median and posterior tibial nerve to assess the motor function of the upper and lower limbs. Sensory nerve study was done for the median and sural nerves to estimate the peripheral neurological function of both upper and lower limbs. F wave study was performed for the upper limb in the median nerve.