Short Term Feeding for Asian Patients With Liver Cirrhosis

University of Malaya

Status: Completed

Conditions: CIRRHOSIS

Treatments: Dietary Supplement: Osmolite and B.C.A.A.; Dietary Supplement: Normal oral intake & supplementation if necessary

Study type: Interventional

Funder types: Other

Identifiers

NCT01165073

NGVOC1

Details and patient eligibility

About

The benefits of short-term naso-gastric feeding in patients with advanced cirrhosis remain uncertain. This was a randomised study comparing naso-gastric feeding and oral feeding in Asian patients with cirrhosis who were admitted to hospital for decompensation.

Full description

Consecutive patients with decompensated cirrhosis who fitted the inclusion criteria, will be randomised to either naso-gastric or oral feeding. Total feeding will be for 2 weeks only. Following intervention specific nutritional and liver-related parameters will be measured during the 2 weeks and up to 6 weeks later. Comparison between both groups will then be made.

Enrollment: 52 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with decompensated cirrhosis of any etiology.

Exclusion criteria

• Advanced hepatic encephalopathy,
• Variceal bleeding,
• Hepatocellular carcinoma.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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52 participants in 2 patient groups

Naso-gastric tube feeding

Experimental group

Treatment:

Dietary Supplement: Osmolite and B.C.A.A.

Oral feeding

Active Comparator group

Treatment:

Dietary Supplement: Normal oral intake & supplementation if necessary