Short Term Refractive and Ocular Parameter Changes After Topical Atropine

Buddhist Tzu Chi Medical Foundation

Status: Completed

Conditions: Myopia, Left Eye

Treatments: Drug: 0.125% Atropine

Study type: Interventional

Funder types: Other

Identifiers

NCT03839888

BuddhistTCGHTaipei2

Details and patient eligibility

About

In order we had designed a prospective clinical trial. Spherical equivalent refractive error (SER), axial length (AL), mean keratometric value (Mean-K), anterior chamber depth (ACD), and intraocular pressure (IOP) were measured at baseline and one week after topical use of 0.125% atropine. Postcycloplegic changes of refractive error and ocular parameters were evaluated, and their correlations were analyzed with multiple linear regression models.

Enrollment: 96 patients

Sex: All

Ages: 3 to 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients who had an SER of -0.5 diopters or less in their eyes.

Exclusion criteria

• Patients who had already been undergoing cycloplegic treatment for myopia before.

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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96 participants in 1 patient group

0.125% atropine group

Experimental group

Description:

patients used the 0.125 % atropine eyedrop every night before sleep for 7 days

Treatment:

Drug: 0.125% Atropine