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Shortened Depression Assessment Study

U

University of Toronto

Status

Completed

Conditions

Depression

Study type

Observational

Funder types

Other

Identifiers

NCT05123794
0032755

Details and patient eligibility

About

Participants will be asked to fill out an online questionnaire about their demographics information and all 42 items from the Depression Anxiety Stress Scale (DASS-42). A series of machine learning techniques will be applied to the dataset to develop a shortened assessment using the most important demographics and DASS-42 items from the original questionnaire, to predict depression levels indicated by DASS-42.

Full description

Clinical depression affects 5-10% of the world population each year and is a serious mental health issue globally. There are many traditional psychological scales that assess levels of depression in adults, where their items are often redundant in the information they carry, and their scoring is not necessarily linear to the item scores. Thus, machine learning techniques can help find the redundancy in the items, as well as the nonlinear relationship between the item scores and the final prediction. Using the Depression Anxiety Stress Scale 42 (DASS-42) as the basis, participants will be asked to fill out an online questionnaire about their demographics information (age, gender, country of residence, race, etc.) and all 42 items of DASS-42 to provide a dataset for this study. Feature selection techniques such as MRMR and Gini feature importance were applied to identify the most important features in the dataset. Then, using machine learning methods such as Logistic Regression, XGBoost, and Ensemble models, models will be fitted on the most important features to develop a shortened depression scale (7-9 items consisting of demographics items and DASS items) that accurately predicted the levels of depression (as measured by the AUC, ROC and F1 scores.

Enrollment

39,000 patients

Sex

All

Ages

18 to 100 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Adults aged 18 and above
  • Must be able to read English
  • Must have access to the Internet worldwide

Exclusion criteria

  • Children aged 17 and under
  • Persons who cannot read English
  • Persons that do not have access to Internet

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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