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Should Integrilin be an Integral Part of Adjunctive Therapy in Patients Undergoing Primary PCI for ST-Elevation MI?

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MedStar Health

Status

Withdrawn

Conditions

ST-elevation Myocardial Infarction
Acute Myocardial Infarction

Study type

Observational

Funder types

Other

Identifiers

NCT01991366
Integrilin Stemi

Details and patient eligibility

About

The aim of this observational study is to evaluate the in hospital and 6 month outcomes of the use of Glycoprotein IIb/IIIa inhibitor eptifibatide as adjunctive therapy in patients undergoing primary Percutaneous Coronary Intervention for ST-elevation myocardial infarction in a large tertiary referral center.

It is hypothesized that Glycoprotein IIb/IIIa inhibitor use during primary Percutaneous Coronary Intervention for ST-elevation myocardial infarction/ acute myocardial infarction is superior to unfractionated heparin alone or bivalirudin alone. Additionally, after propensity matching this superiority remains.

Full description

This is a retrospective, observational, data analysis of approximately 800 patients who underwent primary Percutaneous Coronary Intervention at our institution since September 2000. Patients will have either received eptifibatide pre-or during Percutaneous Coronary Intervention or have received no eptifibatide. Patients who received a thrombolytic prior to Percutaneous Coronary Intervention will be excluded.

This analysis is estimated to take 1-2 months.

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Underwent Percutaneous Coronary Intervention at Washington Hospital Center since September 2000
  • Either received eptifibatide pre-or during PCI or have received no eptifibatide.

Exclusion criteria

  • Patients who received a thrombolytic prior to Percutaneous Coronary Intervention.

Trial design

0 participants in 3 patient groups

Eptifibatide Pre PCI
Description:
Receive eptifibatide pre PCI
Eptifibatide during PCI
Description:
Receive eptifibatide during PCI
No Eptifibatide
Description:
Receive no eptifibatide

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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