Shunt Evaluation With ALPE System in Thoracic Surgery

Università degli Studi di Ferrara

Status: Completed

Conditions: Thoracic Diseases; Mechanical Ventilation

Study type: Observational

Funder types: Other

Identifiers

NCT02968550

SEAT

Details and patient eligibility

About

. The aim of this study, thus, is to evaluate shunt fraction and markers of alveolar distress during one lung ventilation (OLV) at different levels of positive end expiratory pressure (PEEP). Moreover, investigators will focus on predicting factors of high shunt levels during OLV.

Enrollment: 41 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients scheduled for thoracoscopic lobectomy or thoracoscopic wedge resection in lateral decubitus.
• patients American Society of Anesthesiologists Physical Status Classification score of 1-3

Exclusion criteria

• Patients with hemodynamic instability,
• Patients with severe chronic respiratory failure
• Patients with preoperative anemia (hemoglobin <10 g 100 ml-1)
• Patients requiring unplanned conversion to thoracotomy

Trial design

41 participants in 2 patient groups

Low shunt group

Description:

patients with shunt less than 30% in one-lung ventilation at ZEEP

High shunt group

Description:

Patients with shunt equal or more than 30% in one-lung ventilation at ZEEP