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Sickle Cell Disease, Neurocognitive Disorders, Social Participation (SOCIODREP)

C

Centre Hospitalier Universitaire de Pointe-a-Pitre

Status

Completed

Conditions

Sickle Cell Disease

Treatments

Other: Measure of the Life habits (MHAVIE)

Study type

Observational

Funder types

Other

Identifiers

NCT04793854
PAP_RNI_2018/02

Details and patient eligibility

About

This project will promote the development of transdisciplinary analyses. Neuropsychological disorders will be explored with the usual appropriate tests done by psychologists and neuropsychologists regularly involved in the management of sickle cell disease affected children. For the social sciences' component, various methods will be used: Measure of the Life habits (MHAVIE), Measure of Environmental Quality (MQE) and semi-guided interviews will complete the collection of qualitative data. The expected results concern the identification of the barriers or facilitators the sickle cell patients might face in their social participation, whether they are affected or not by neurological disorders.

Full description

Sickle cell anaemia, which is the most frequent genetic disease in France, requires an early and optimal care to reduce its morbidity and mortality. Children with sickle cell anaemia who are significantly anaemic may present neurological complications including stroke with or without clinical signs. A major risk associated to these strokes is the impairment of the general intellectual ability and learning ability, essentially resulting from neuropsychological disorders affecting intellectual functioning, executive and attentional functions. Although the negative impact of sickle cell anemia on the quality of life of the affected children and adolescents is well documented, no study has been focused on the role played by the neurocognitive disorders on their social participation. The objective of this project is the assessment of the influence of neurocognitive disorders in the social participation of children and adolescent with sickle cell anemia (6 to 16 years old), followed in Guadeloupe. This project will promote the development of transdisciplinary analyses. Neuropsychological disorders will be explored with the usual appropriate tests done by psychologists and neuropsychologists regularly involved in the management of sickle cell disease affected children. For the social sciences' component, various methods will be used: Measure of the Life habits (MHAVIE), Measure of Environmental Quality (MQE) and semi-guided interviews will complete the collection of qualitative data. The expected results concern the identification of the barriers or facilitators the sickle cell patients might face in their social participation, whether they are affected or not by neurological disorders

Enrollment

134 patients

Sex

All

Ages

6 to 16 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Sickle cell anemia
  • Age between 6 and 16 years inccuded, attending the centre of reference for sickle cell disease in Guadeloupe
  • Informed consent
  • Medical insurance

Exclusion criteria

  • Other sickle cell syndrome other than SS or Sb-thal
  • Less than 6 years old or older than 16
  • Attending other sickle cell departments
  • No medical insurance

Trial design

134 participants in 2 patient groups

Case
Description:
Children with sickle cell anemia attending the centre of reference for sickle cell disease in Guadeloupe.
Treatment:
Other: Measure of the Life habits (MHAVIE)
Control
Description:
Control children without chronical disease
Treatment:
Other: Measure of the Life habits (MHAVIE)

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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