Silodosin in Management of Lower Ureteral Stones

Syrian Private University

Status and phase: Completed; Phase 2; Phase 1

Conditions: Stone, Kidney

Treatments: Drug: Silodosin

Study type: Interventional

Funder types: Other

Identifiers

NCT06381206

No 475

Details and patient eligibility

About

This research aims to study the effectiveness of silodosin in the management of lower ureter stones larger than 6 mm in diameter in terms of affected ureter (right or left), the size of the stone, the degree of hydronephrosis, the rate of stone expulsion(day), whether the stone was completely expelled or not, and the side effects of silodosin.

Enrollment: 100 patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients attending the urology Clinic with a distal unilateral ureteral stone larger than 6 mm in diameter.

Exclusion criteria

• Patients under 18 years of age
• Pregnant women
• Patients with whom we were unable to contact
• Patients treated with silodosin for another reason
• Single kidney patients
• Patients with bilateral ureter stones
• Patients with deteriorating kidney function
• Patients with grades 3rd and 4th of hydronephrosis

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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100 participants in 2 patient groups

case group

Experimental group

Description:

patients who had given silodosin

Treatment:

Drug: Silodosin

Control group

No Intervention group

Description:

patients who had not given silodosin