Simultaneous Integrated Boost Technique in Breast Cancer Radiotherapy

M

Medical University of Graz

Status

Withdrawn

Conditions

Radiotherapy Side Effect
Breast Cancer

Treatments

Radiation: Simultaneous integrated boost

Study type

Interventional

Funder types

Other

Identifiers

NCT04535895
1094/2020

Details and patient eligibility

About

Adjuvant radiotherapy after breast conserving surgery has been shown to improve both local control and overall survival. Dose escalation of the tumor bed by addition of a boost after whole breast radiotherapy reduces the risk of local recurrence in invasive breast cancer. Simultaneous integrated boost (SIB) techniques have been shown to provide more conformal treatment plans than conventional sequential boost, in addition, SIB enables a reduction in the overall treatment time by 1 week compared to conventional boost techniques. The proposed study is aimed at evaluating radiation-induced toxicity in patients treated with breast-conserving surgery in combination with radiotherapy using SIB technique.

Sex

Female

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Invasive breast cancer or ductal carcinoma in situ
  • Breast conserving surgery
  • Complete tumor resection
  • Treatment with adjuvant radiotherapy of the breast
  • Indication for boost Irradiation
  • Given informed consent

Exclusion criteria

  • Incomplete tumor resection
  • Mastectomy
  • Distant metastases at diagnosis
  • Unable to give informed consent

Trial design

Primary purpose

Treatment

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

0 participants in 1 patient group

Simultaneous integrated boost arm
Experimental group
Treatment:
Radiation: Simultaneous integrated boost

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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