Simvastatin Reduces Adiponectin Levels and Insulin Sensitivity

Gachon University Gil Medical Center

Status: Completed

Conditions: Hypercholesterolemia

Study type: Observational

Funder types: Other

Identifiers

NCT00546182

GMC-200405

Details and patient eligibility

About

We hypothesized simvastatin may reduce adiponectin levels and insulin sensitivity in overweight hypercholesterolemic patients.

Sex: All

Ages: 25 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Low-density lipoprotein cholesterol levels more than 100 and body mass index more than 23.0

Exclusion criteria

• Patients with overt liver disease
• Chronic renal failure
• Hypothyroidism, myopathy
• Uncontrolled diabetes
• Severe hypertension, stroke
• Acute coronary events
• Coronary revascularization within the preceding 3 months, or
• Alcohol abuse.