Simvastatin Versus MTA in Pulpotomy of Immature Permanent Molars

Ahmad Elheeny

Status and phase: Enrolling; Early Phase 1

Conditions: Pulp Exposure, Dental

Treatments: Drug: Simvastatin

Study type: Interventional

Funder types: Other

Identifiers

NCT05878158

300

Details and patient eligibility

About

the study will be done to evaluate the clinical and digital radiographic success of simvastatin versus MTA in pulpotomy of immature permanent molars

Full description

the clinical and digital radiographic success of simvastatin versus MTA in pulpotomy of immature permanent molars for the following patients which include: Healthy children aged from 6 to 8 years who will be classified as Class I or II Children according to the American Society of Anaesthesiologists (ASA) will be included. Children with severe behavioral, or emotional disabilities, and medically compromised children will be excluded.

Enrollment: 128 estimated patients

Sex: All

Ages: 6 to 8 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Healthy children aged from 6 to 8 years
• Children with severe behavioral, or emotional disabilities, and medically compromised children will be excluded.
• Deep carious lesions of the first permanent immature molars with signs & symptoms of reversible pulpitis will be included
• Normal radiographic findings and immature roots

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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128 participants in 2 patient groups

simvastatin

Active Comparator group

Description:

Drug The drug powder will be mixed with distilled water to form a paste applied in the pup chamber of immature permanent molars over the pulp stump

Treatment:

Drug: Simvastatin

Mineral Trioxide Aggregate

Experimental group

Description:

Dental material It is a regenrative endodontic material prepared as apoweder that mixed with distilled water to form a paste applied in the pup chamber of immature permanent molars over the pulp stump

Treatment:

Drug: Simvastatin