Single Adductor-canal-block Versus Peri-articular Infiltration on Outcome After Total Knee Arthroplasty

Chinese Academy of Medical Sciences & Peking Union Medical College

Status: Unknown

Conditions: Osteoarthritis,Knee

Treatments: Drug: periarticular infiltration; Drug: single adductor-canal-block

Study type: Interventional

Funder types: Other

Identifiers

NCT02784041

ZS-980

Details and patient eligibility

About

The purpose of this study is to compare the effect of single adductor-canal-block versus single femoral nerve block on the recovery after total knee arthroplasty.

Full description

The aim of this study is to assess the effect of different analgesic effects on the outcome of patients undergoing total knee arthroplasty. Patients who will have primary unilateral total knee replacement between September 2016 to June 2018 at Peking Union Medical College Hospital and meet the inclusion criteria will be included. They are randomized into two groups. The total knee arthroplasty is performed by one surgeon and adductor-canal block is performed by one anesthesiologist who is not responsible for follow-up. Patients on both groups will have intravenous patient control analgesia with 1 mg morphine/bolus. One residency is responsible for the follow-up.

Enrollment: 200 estimated patients

Sex: All

Ages: 45 to 85 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• osteoarthritis
• unilateral total knee arthroplasty
• ASA grade I - II
• normal cognitive function.

Exclusion criteria

• patients refuse
• BMI > 35
• diagnosis other than osteoarthritis
• allergy to the drugs used or contraindication to the intervention

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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200 participants in 2 patient groups

single adductor-canal-block

Experimental group

Description:

Patients in this group will receive ultrasound guided single adductor-canal- block with 0.35% ropivacaine 25ml.

Treatment:

Drug: single adductor-canal-block

periarticular infiltration

Experimental group

Description:

patients in this group will receive periarticular infiltration of local anesthetic.

Treatment:

Drug: periarticular infiltration