Single and Double DNA Strand Breaks in Males With Unexplained Infertility Attending Fertility Treatment

Peter Humaidan

Status: Enrolling

Conditions: Infertility, Male

Treatments: Other: Sperm DNA Fragmentation

Study type: Observational

Funder types: Other

Identifiers

NCT05846256

Doublestrand DNA Fragmentation

Details and patient eligibility

About

The aim of this study is to investigate the extent of double-stranded DNA damage in sperm in men with unexplained infertility.

Enrollment: 125 estimated patients

Sex: Male

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Unexplained infertile men who will undergo 1st or 2nd IVF treatment
• Age over 18 years
• Normal sperm parameters according to WHO criteria
• IVF treatment

Exclusion criteria

• ICSI

Trial design

125 participants in 2 patient groups

Infertile male

Description:

Men with unexplained infertility

Treatment:

Other: Sperm DNA Fragmentation

Donors (control)

Description:

Fertile sperm donors

Treatment:

Other: Sperm DNA Fragmentation