Single Application of Desensitizing Pastes as Dentin Sensitivity Treatment

Federal University of São Paulo

Status: Completed

Conditions: Dentine Hypersensitivity

Treatments: Procedure: Sensodyne; Procedure: Nano P; Procedure: Cocorico; Procedure: Colgate

Study type: Interventional

Funder types: Other

Identifiers

NCT02018783

dessensibilizantes

Details and patient eligibility

About

The aim of this study was to evaluate the efficacy of three desensitizing toothpastes for immediate and intermediate-term relief of CDH, when compared with a control toothpaste. One hundred and thirty-eight hypersensitive teeth were diagnosed and randomized into four groups according to the therapeutic agent of each desensitizing cream tested: 1) strontium acetate and calcium carbonate, 2) calcium carbonate and arginine 8%, 3) calcium phosphate nanoparticles and 4) a control toothpaste. The desensitizing creams were applied according to the manufacturer's instructions. Cervical dentin hypersensitivity was assessed at baseline, immediately, 24 hours and 30 days after the treatment. Cold and evaporative tests were used to assess the sensitivity level.

Enrollment: 138 patients

Sex: All

Ages: 22 to 48 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• subjects 18 years or older
• in good general and oral health; have complaint of CDH in teeth distributed in all 4 quadrants
• not making use of desensitizing agents
• not having undergone periodontal treatment over the past 3 months
• respond to evaporative stimulus with a score ≥ 1.5 cm on VAS

Exclusion criteria

• patients who presented restorations and caries near the exposed dentin of the hypersensitive teeth
• who made frequent use of painkillers, anti-inflammatory and antidepressants drugs

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Triple Blind

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138 participants in 4 patient groups, including a placebo group

Sensodyne

Experimental group

Description:

Digital application for 60 seconds.

Treatment:

Procedure: Sensodyne

Colgate

Experimental group

Description:

Slow-speed handpiece with a Robson brush for 3 seconds by repeating the procedure

Treatment:

Procedure: Colgate

Nano P

Experimental group

Description:

Slow-speed handpiece with a Robson brush for 10 seconds

Treatment:

Procedure: Nano P

Cocorico

Placebo Comparator group

Description:

Digital application for 60 seconds

Treatment:

Procedure: Cocorico