Single Blind Randomized Study to Determine the Sensitivity and Specificity of 2 Non-invasive Markers of Early Coronary Disease

McGill University

Status: Terminated

Conditions: Coronary Artery Disease

Study type: Observational

Funder types: Other

Identifiers

NCT01742156

OPTH-CAD

Details and patient eligibility

About

Diagonal ear lobe crease and microcirculatory disorder in the conjunctiva are both non invasive methods documented in the literature as early signs of coronary artery disease. We wish to study the sensitivity and specificity of both signs by conducting a single blind study involving patients with documented presence or absence of coronary artery disease via angiogram.

Enrollment: 10 patients

Sex: All

Ages: 20 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age 20 to 70 years old
• angiogram within past 12 weeks
• stable during post angio period
• willing to provide informed consent

Exclusion criteria

• previous eye surgery including cataract surgery
• previous ophthalmologic disorders
• previous surgeries involving ears or ear lobes

Trial design

10 participants in 2 patient groups

Presence of coronary disease

Description:

All patients with or without coronary disease who are followed in coronary clinics or wards

coronary disease

Description:

Is coronary disease associated with tortuosity of vessels Patients seen in cardiology clinics