Single Bolus Intravenous Ephedrine Attenuates Reduction of Core Body Temperature in Patients Undergoing Spinal Anesthesia for Arthroscopic Knee and Ankle Surgery

Mahidol University

Status

Completed

Conditions

Body Temperature Changes

Treatments

Drug: NSS

Drug: Ephedrine

Study type

Interventional

Funder types

Other

Identifiers

NCT02948920

07-59-07

TCTR20161017007 (Registry Identifier)

Details and patient eligibility

About

A prospective double-blinded randomized controlled study to determine efficacy of ephedrine in preserving core temperature in patients under neuraxial spinal anesthesia for knee and ankle arthroscopic surgery.

Full description

To determine the effect of ephedrine on preserving core temperature (tympanic) when given at finishing of local anesthetic administration for spinal neuraxial anesthesia comparing to normal saline (120 minutes period)

Enrollment

40 patients

Sex

All

Ages

18 to 70 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patient undergoing knee or ankle arthroscopic surgery under spinal block at department of orthopaedic Ramathibodi Hospital
BMI 17-30 kg/m2
ASA physical status 1-3
Age 18-70
Last oral intake more than 6 hours (2 hours for water)
Consent form acquired

Exclusion criteria

Patient who are contraindicated for spinal block
Anesthesia level higher than T4 or lower than T10
Tympanic temperature more than 37.5 or less than 35.5 degrees Celsius
Otitis or other ear infection
Patients who receive alpha adrenergic blocker or beta adrenergic blocker
Initial blood pressure presenting in operating theater 140 90 mmHg repeat after rest 5 minutes
Patient refusal