Single-stage ERCP and Laparoscopic Cholecystectomy for Cholecystocholedocholithiasis: Which to Start With?

Assiut University

Status: Completed

Conditions: Biliary Stones; Choledocholithiasis With Cholecystitis

Treatments: Procedure: Endoscopic Retrograde Cholangiopancreatography (ERCP); Procedure: Laproscopic cholecystectomy (LC)

Study type: Observational

Funder types: Other

Identifiers

NCT06340594

RF-2-2024

Details and patient eligibility

About

Chronic calculous cholecystitis is associated with common bile duct (CBD) stones in approximately 12% of patients. These patients need both cholecystectomy and CBD clearance of stones. The standard for cholecystectomy is laparoscopic cholecystectomy (LC) and the mostly common treatment used for CBD clearance is Endoscopic Retrograde Cholangiopancreatography (ERCP). The two interventions can be combined to be done at the same time under single anesthesia session. Studies of single stage ERCP+LC showed confirmed the safety and efficacy of the combined technique. However, some surgeons start with the ERCP while others start with LC.The aim of this study is to compare the start with ERCP followed by LC to the start with LC followed by ERCP when the two techniques are combined at the same session for treatment of chronic calculous cholecystitis associated with CBD stones regarding efficacy and safety of the two approaches.

Enrollment: 115 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients underwent single stage ERCP+LC for cholecystocholedocholithiasis

Exclusion criteria

• Contraindications to ERCP, or laparoscopic surgery
• Cholangitis and pancreatitis
• Previously failed ERCP

Trial design

115 participants in 2 patient groups

Group A (ERCP 1st approach)

Description:

The patients first underwent ERCP followed by standard 4 port LC.

Treatment:

Procedure: Endoscopic Retrograde Cholangiopancreatography (ERCP)

Procedure: Laproscopic cholecystectomy (LC)

Group B (LC 1st approach)

Description:

The patients first underwent LC followed by ERCP.

Treatment:

Procedure: Endoscopic Retrograde Cholangiopancreatography (ERCP)

Procedure: Laproscopic cholecystectomy (LC)